Publications

  • Cobalt-Catalyzed Syntheses of Esters and Carboxylic Acids from Alkenes Promoted by Light

    Mason S. Faculak, Michael R. Rodriguez, Erik J. Alexanian

    J. Am. Chem. Soc. 2025, ASAPs

  • Synthesis of Acid Anhydrides via the Thermal or Photochemical Catalytic Hydrocarbonylation of Alkenes

    Alexander M. Veatch, Shrabanti Bhattacharya, Mason S. Faculak, Drew W. Cunningham, Jeffrey A. Bennett, Malek Y. S. Ibrahim, Mesfin E. Janka, Dawn C. Mason, Javier M. Grajeda, Milad Abolhasani, Nathan M. West, Erik J. Alexanian, Alexander J. M. Miller

    ACS Catal. 2025, 15, 3, 2576–2583

  • Homologation of Carboxylic Acids Using a Radical-Polar Conjunctive Reagent

    Jonathan N. Gruhin, Richard Kim, Aristidis Vasilopoulos, Eric A. Voight, Erik J. Alexanian

    J. Am. Chem. Soc. 2024, 146, 48, 32919–32924.

  • C(sp3)–H (N-Phenyltetrazole)thiolation as an Enabling Tool for Molecular Diversification

    Ashley Zachmann, Justine Drappeau, Shubin Liu, Erik John Alexanian

    Angew. Chem. Int. Ed. 2024, e202404879.

  • Cobalt-Catalyzed Synthesis of Amides from Alkenes and Amines Promoted by Light

    Mason S. Faculak, Alexander M. Veatch, and Erik J. Alexanian

    Science 2024, 383, 77-81.

  • C–H Functionalization of Polyolefins to Access Reprocessable Polyolefin Thermosets

    Eliza K. Neidhart, Mutian Hua, Zhengxing Peng, Logan T. Kearney, Vittal Bhat, Foad Vashahi, Erik J. Alexanian, Sergei S. Sheiko, Cheng Wang, Brett A. Helms, and Frank A. Leibfarth

    J. Am. Chem. Soc. 2023, 145, 50, 27450–27458.

  • General Synthesis of N-Alkylindoles from N,N-Dialkylanilines via [4 + 1] Annulative Double C–H Functionalization

    Bowen Zhang, Frederik R. Erb, Aristidis Vasilopoulos, Eric A. Voight, and Erik J. Alexanian

    J. Am. Chem. Soc. 2023, 145, 49, 26540–26544.

  • Modifying Poly(caprolactone) Degradation through C–H Functionalization

    Victoria J. Barber, Meredith A. Borden, Jill W. Alty, Ly D. Tran, Hilmar Koerner, Luke A. Baldwin, Erik J. Alexanian, and Frank A. Leibfarth

    Macromolecules 2023, 56, 10, 3679–3686.

  • Cobalt-Catalyzed Deaminative Amino- and Alkoxycarbonylation of Aryl Trialkylammonium Salts Promoted by Visible Light

    Alexander Veatch, Shubin Liu, Erik John Alexanian

    Angew. Chem. Int. Ed. 2022, 61, e202210772.

  • Heteroarylation of unactivated C–H bonds suitable for late-stage functionalization

    Austin S. Miller, Erik J. Alexanian

    Chem. Sci. 2022, 13, 11878-11882.

  • Diversification of aliphatic C–H bonds in small molecules and polyolefins through radical chain transfer

    Timothy J. Fazekas, Jill W. Alty, Eliza K. Neidhart, Austin S. Miller, Frank A. Leibfarth, Erik J. Alexanian

    Science 2022, 375, 545-550.

  • Stereospecific Nickel-Catalyzed Reductive Cross-Coupling of Alkyl Tosylate and Allyl Alcohol Electrophiles

    Quentin D. Tercenio, Erik J. Alexanian

    Org. Lett. 2021, 23, 7215-7219.

  • Cobalt-catalyzed Aminocarbonylation of (Hetero)aryl Halides Promoted by Visible Light

    Alexander M. Veatch, Erik J. Alexanian

    Chem. Sci. 2020, 11, 7210-7213.

  • Direct Decarboxylative Functionalization of Carboxylic Acids via O-H Hydrogen Atom Transfer

    Christina G. Na, Davide Ravelli, Erik J. Alexanian

    J. Am. Chem. Soc. 2020, 142, 44-49.

  • Manganese-Catalyzed Stereospecific Hydroxymethylation of Alkyl Tosylates

    Hannah Shenouda, Erik J. Alexanian

    Org. Lett. 2019, 21, 9268-9271.

  • Identifying Amidyl Radicals for Intermolecular C-H Functionalizations

    Special Issue on C-H Bond Functionalization

    Matthew M. Tierney, Stefano Crespi, Davide Ravelli, Erik. J. Alexanian

    J. Org. Chem. 2019, 84, 12983-12991.

  • C-H Alkylation via Multisite Proton-Coupled Electron Transfer of an Aliphatic C-H Bond

    Carla M. Morton, Qilei Zhu, Hunter Ripberger, Ludovic Troian-Gautier, Zi S. D. Toa, Robert R. Knowles, Erik J. Alexanian

    J. Am. Chem. Soc. 2019, 141, 13253-13260.

  • Chemo- and Regioselective Functionalization of Isotactic Polypropylene: A Mechanistic and Structure-Property Study

    Jill B. Williamson, Christina G. Na, Robert R. Johnson III, William F. M. Daniel, Erik J. Alexanian, Frank A. Leibfarth

    J. Am. Chem. Soc. 2019, 141, 12815-12823.

  • Nickel-Catalyzed, Ring-Forming Aromatic C-H Alkylations with Unactivated Alkyl Halides

    Special Issue in honor of Prof. John Hartwig’s 2018 Tetrahedron Prize

    Quentin D. Tercenio, Erik J. Alexanian

    Tetrahedron 2019, 75, 4143-4149.

  • Cobalt-Catalyzed Aminocarbonylation of Alkyl Tosylates: Stereospecific Synthesis of Amides

    Brendon T. Sargent, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2019, 58, 9533-9536.

  • Transition-Metal (Pd, Ni, Mn)-Catalyzed C-C Bond Constructions Involving Unactivated Alkyl Halides and Fundamental Synthetic Building Blocks

    Megan R. Kwiatkowski, Erik. J. Alexanian

    Acc. Chem. Res. 2019, 52, 1134-1144.

  • Nickel-Catalyzed Mizoroki-Heck-Type Reactions of Unactivated Alkyl Bromides

    Megan R. Kwiatkowski, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2018, 57, 16857-16860.

  • A General Approach to Site-Specific, Intramolecular C-H Functionalization Using Dithiocarbamates

    Christina G. Na, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2018, 57, 13106-13109.

  • Reagent-Dictated Site Selectivity in Intermolecular Aliphatic C-H Functionalizations Using Nitrogen-Centered Radicals

    Anthony M. Carestia, Davide Ravelli, Erik J. Alexanian

    Chem. Sci. 2018, 9, 5360-5365.

  • Regioselective C-H Xanthylation as a Platform for Polyolefin Functionalization

    Jill B. Williamson, William L. Czaplyski, Erik J. Alexanian, Frank A. Leibfarth

    Angew. Chem. Int. Ed. 2018, 57, 6261-6265.

  • A General Strategy for Aliphatic C-H Functionalization Enabled by Organic Photoredox Catalysis

    Kaila A. Margrey, William L. Czaplyski, David A. Nicewicz, Erik J. Alexanian

    J. Am. Chem. Soc. 2018, 140, 4213-4217.

  • Cobalt-Catalyzed Carbonylative Cross-Coupling of Alkyl Tosylates and Dienes: Stereospecific Synthesis of Dienones at Low Pressure

    Brendon T. Sargent, Erik J. Alexanian

    J. Am. Chem. Soc. 2017, 139, 12438-12440.

  • Palladium-Catalyzed Carbocyclizations of Unactivated Alkyl Bromides with Alkenes Involving Auto-tandem Catalysis

    Alexander R. O. Venning, Megan R. Kwiatkowski, Joan E. Roque Pena, Brendan C. Lainhart, Akil A. Guruparan, Erik J. Alexanian

    J. Am. Chem. Soc. 2017, 139, 11595-11600.

  • Cobalt-Catalyzed Silylcarbonylation of Unactivated Secondary Alkyl Tosylates at Low Pressure

    Joan E. Roque Pena, Erik J. Alexanian

    Org. Lett. 2017, 19, 4413-4415.

  • A General Approach to Quaternary Center Construction from Couplings of Unactivated Alkenes and Acyl Xanthates

    Ernest N. Jenkins, William L. Czaplyski, Erik J. Alexanian

    Org. Lett. 2017, 19, 2350-2353.

  • C-H Xanthylation: A Synthetic Platform for Alkane Functionalization

    William L. Czaplyski, Christina G. Na, Erik J. Alexanian

    J. Am. Chem. Soc. 2016, 138, 13854-13857.

  • Manganese-Catalyzed Carboacylations of Alkenes with Alkyl Iodides

    Caitlin M. McMahon, Matthew S. Renn, Erik J. Alexanian

    Org. Lett. 2016, 18, 4148-4150.

  • Palladium-Catalyzed Alkoxycarbonylation of Unactivated Secondary Alkyl Bromides at Low Pressure

    Brendon T. Sargent, Erik J. Alexanian

    J. Am. Chem. Soc. 2016, 138, 7520-7523.

  • Site-Selective Aliphatic C­H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide

    Ryan Quinn, Zef Könst, Sharon Michalak, Yvonne Schmidt, Anne Szklarski, Alex Flores, Sangkil Nam, David Horne, Christopher Vanderwal, Erik Alexanian

    J. Am. Chem. Soc. 2016, 138, 696-702.

  • Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides

    Alexander R.O. Venning , Patrick T. Bohan , Erik J. Alexanian

    J. Am. Chem. Soc. 2015, 137, 3731–3734.

  • Stereoselective Nickel-Catalyzed [2+2] Cycloadditions of Ene-Allenes

    Njamkou N. Noucti, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2015, 54, 5447-5450.

  • Enantioselective Synthesis of cis-Fused Cyclooctanoids via Rhodium(I)-Catalyzed [4+2+2] Cycloadditions

    Brendan C. Lainhart, Erik J. Alexanian

    Org. Lett. 2015, 17, 1284–1287.

  • Site-Selective Aliphatic C–H Bromination Using N-Bromoamides and Visible Light

    Valerie A. Schmidt, Ryan K. Quinn, Andrew T. Brusoe, Erik J. Alexanian

    J. Am. Chem. Soc. 2014, 136, 14389-14392.

  • Alkene Hydrofunctionalization Using Hydroxamic Acids: A Radical Mediated Approach to Alkene Hydration

    Benjamin C. Giglio, Erik J. Alexanian

    Org. Lett. 2014, 16, 4304-4307.

  • Palladium-Catalyzed Heck-Type Cross-Couplings of Unactivated Alkyl Iodides

    Caitlin M. McMahon, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2014, 53, 5974-5977.

  • Radical Carbooxygenations of Alkenes Using Hydroxamic Acids

    Ryan K. Quinn, Valerie A. Schmidt, Erik J. Alexanian

    Chem. Sci. 2013, 4, 4030-4034.

  • Stereoselective Nickel-Catalyzed [2+2+2] Cycloadditions and Alkenylative Cyclizations of Ene-Allenes and Alkenes

    Njamkou N. Noucti, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2013, 52, 8424-8427.

  • Enantioselective Intermolecular [2+2+2] Cycloadditions of Ene-Allenes with Allenoates

    Andrew T. Brusoe, Rahul V. Edwankar, Erik J. Alexanian

    Org. Lett. 2012, 14, 6096-6099.

  • Metal-Free, Aerobic Ketooxygenation of Alkenes Using Hydroxamic Acids

    Valerie A. Schmidt, Erik J. Alexanian

    Chem. Sci. 2012, 3, 1672-1674.

  • Palladium-Catalyzed Heck-Type Reactions of Alkyl Iodides

    Kayla S. Bloome, Rebecca L. McMahen, Erik J. Alexanian

    J. Am. Chem. Soc. 2011, 133, 20146-20148.

  • Metal-Free, Aerobic Dioxygenation of Alkenes Using Simple Hydroxamic Acid Derivatives

    Benjamin C. Giglio, Valerie A. Schmidt, Erik J. Alexanian

    J. Am. Chem. Soc. 2011, 133, 13320-13322.

  • Metal-Free Oxyaminations of Alkenes Using Hydroxamic Acids

    Valerie A. Schmidt, Erik J. Alexanian

    J. Am. Chem. Soc. 2011, 133, 11402-11405.

  • Rhodium(I)-Catalyzed Ene-Allene-Allene [2+2+2] Cycloadditions: Stereoselective Synthesis of Complex trans-Fused Carbocycles

    Andrew T. Brusoe, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2011, 123, 6726-6730.

  • Palladium-Catalyzed Carbonylative Heck-Type Reactions of Alkyl Iodides

    Kayla S. Bloome, Erik J. Alexanian

    J. Am. Chem. Soc. 2010, 132, 12823-12825.

  • Metal-Free, Aerobic Dioxygenation of Alkenes Using Hydroxamic Acids

    Valerie A. Schmidt, Erik J. Alexanian

    Angew. Chem. Int. Ed. 2010, 49, 4491-4494.

Alexanian Publications (Graduate and Post-Doc)